Eprinomectin is an avermectin with anthelmintic and insecticidal activities.Eprinomectin is a semisynthetic avermectin that consists of a mixture of two homologues, eprinomectin B1a (4 epi-acetylamino-4 -deoxy-avermectin B1; 90%) and eprinomectin B1b (10%).Eprinomectin was developed as a topical endectocide for all categories of cattle including lactating dairy cattle, and the process by which eprinomectin was selected for further development has been described (90). Briefly, several hundred avermectin/ milbemycin analogues were screened in a sheep model for efficacy against a range of endoparasites and in lactating dairy cows for a low milk:plasma partitioning ratio. Themilk:plasma ratio for eprinomectin is <0.2; ivermectin, by comparison, partitions equally between milk and plasma.
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Eprinomectin
is an
a
bam
ectin
used as a veterinary
topical
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endectocide
. It is a mixture of two chemical compounds, eprinomectin B1a and B1b.
Eprinomectin
is a highly effective, broad-spectrum, and low-residue veterinary anthelmintic drug that is the only broad-spectrum anthelmintic drug applied to lactating dairy cows without the need for milk abandonment and without the need for a rest period
.
Eprinomectin
has a good control effect in the control of internal and ectoparasites such as nematodes, hookworms, ascaris, helminths, insects and mites in various animals such as cattle, sheep, camels, and rabbits. It is mainly used for the treatment of gastrointestinal nematodes, itching mites and sarcoptic mange in livestock.
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